Skip to main content

ARTEROLANE - PIPERAQUINE

 ARTEROLANE+ PIPERAQUINE



BRAND NAME:- Synriam ( arterolane malate 150mg + piperaquine 750mg ) 



ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE together treats malaria. They work by increasing the levels of heme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.

       ARTEROLANE - PIPERAQUINE FDC has undergone multicentric clinical trials in India 🇮🇳, Bangladesh and Thailand. In uncomplicated falciparum malaria 🦟 this ACT has produced ≥ 95% cure rates with a fever and parasitaemia  clearance time 24-28 hours. In a comparative trail its efficacy and tolerability has been found equivalent to artemether - LUMEFANTRINE. 


Thus arterolane - piperaquine appears to be an effective and well tolerated alternative ACT. 


 

USED:- treatment of malaria 🦟.



SIDE EFFECTS:-  are generally mild headache, postural dizziness, vomiting, abdominal pain and Diarrhoea.



DOSE:- 1 CAP. OD for 3 days.






Labels:

Comments

Post a Comment

Popular posts from this blog

Know details about Dabigatran etexilate drug ?

 Dabigatran Etexilate 
Post a Comment
Read more

Chlorthalidone Uses, Side Effects, and More....

 Chlorthalidone  Brand name:- Hythalton 50,100mg , Hydrazide, Thalizide ( 12.5, 25) . Chlorthalidone is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow. Pharmacodynamic:- Not 🚫 available.  Pharmacokinetics:- Chlortalidone is slowly absorbed from the gastrointestinal tract after oral ingestion. It has a long half-life and therefore a prolonged diuretic action, which results in continued diuretic effects despite a skipped dose. This prolonged action of chlortalidone despite missing doses may account for the higher efficacy of chlortalidone compared to the shorter half-life medication, hydrochlorothiazide. Chlortalidone is eliminated from the body mostly by the kidney, as unchanged drug. Thus, in persons with diminished kidney function, the clearance of chlortalidone is reduced and the elimination half-life is increased. As with other thiazide diuretics, ch...
Post a Comment
Read more

Captopril Uses, Side Effects, and More

 Captopril Brand name:- Angiopril 25mg tab, Aceten, Captopril 12.5, 25mg tab. Captopril is an angiotensin converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessel so that blood flows more smoothly and the heart can pump blood more efficiently. Pharmacodynamic:-  Captopril, an ACE inhibitor, antagonizes the effect of the RAAS. The RAAS is a homeostatic mechanism for regulating hemodynamics, water and electrolyte balance. During sympathetic stimulation or when renal blood pressure or blood flow is reduced, renin is released from the granular cells of the juxtaglomerular apparatus in the kidneys. In the blood stream, renin cleaves circulating angiotensinogen to ATI, which is subsequently cleaved to ATII by ACE. ATII increases blood pressure using a number of mechanisms. First, it stimulates the secretion of aldosterone from the adrenal cortex. Aldosterone travels to the distal convoluted tubule (DCT) and collecting tubule of nephrons w...
Post a Comment
Read more