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AMOXAPINE

 AMOXAPINE


BRAND NAME:- Amoxipaine tab,DEMOLOX 50,100mg tab. etc many brands available in India.



Amoxapine is in a class of medications called tricyclic antidepressants (TCAs). It works by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. 


ACTION:- This tetracycline compound is unusual in that it blocks  dopamine D2 receptors in addition to inhibiting NA reuptake . It is chemically related to the antipsychotics drug loxapine and has mixed antidepressant+ neuroleptics properties — offers advantage for patients with psychotic depression. 


USED:- in symptoms of depression.


SIDE EFFECTS:- risk of extrapyramidal is also there. Seizures ( including status epilepticus ) occur in its overdose. 



DOSE:- 100-300mg daily.

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