AMOXAPINE
BRAND NAME:- Amoxipaine tab,DEMOLOX 50,100mg tab. etc many brands available in India.
Amoxapine is in a class of medications called tricyclic antidepressants (TCAs). It works by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance.
ACTION:- This tetracycline compound is unusual in that it blocks dopamine D2 receptors in addition to inhibiting NA reuptake . It is chemically related to the antipsychotics drug loxapine and has mixed antidepressant+ neuroleptics properties — offers advantage for patients with psychotic depression.
USED:- in symptoms of depression.
SIDE EFFECTS:- risk of extrapyramidal is also there. Seizures ( including status epilepticus ) occur in its overdose.
DOSE:- 100-300mg daily.
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