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ALPROSTADIL (PGE1)(MUSE)

 ALPROSTADIL


BRAND NAME:- muse,prostin,Edex & etc.



ALPROSTADIL is used to treat erectile dysfunction (impotence) and to help diagnose certain causes of this disorder. Alprostadil is also used to improve blood flow in newborn babies with heart problems. This medication guide addresses only the adult male use of alprostadil in erectile disorders.




MECHANISM & PHARMACOLOGICAL ACTION:-

Alprostadil (PGE1) injected  directly into the corpus cavernous using a fine needle produces erection lasting 1-2 hours to permit intercourse. Alprostadil injections are less painful than papaverine,but local tenderness may occur. Penile fibrosis and priapism are rare. It is now the most commonly used drug in patients not responding to PDE-5 inhibitors,such as neurogenic and psychogenic ED.

Alprostadil relaxes blood vessels and muscles in the penis which increases blood flow, causing an erection.

Alprostadil may also be used for purposes not listed in this medication guide.


USES & DOSE 

1.Alprostadil is used only when needed. An erection should occur within 5 to 20 minutes and last up to 60 minutes.

2.Alprostadil injection is injected into the side of the penis.

3.Alprostatil transurethral pellet is a very small suppository to be inserted into the opening of the penis (the urethra). 


Note:-Ask your doctor or pharmacist if you don't understand how to use the injection.


WARNING ⚠️:-

Do not use more than 2 pellets in one day. Do not use more than 3 injections per week. Wait at least 24 hours between each . 


SIDE EFFECTS:-Overdose can cause fainting, or a painful and prolonged erection. 

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