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ACETYLCYSTEINE

ACETYLCYSTEINE


BRAND NAME:- Acetadote ,Fluimucil & others

ACTION:-Acetylcysteine, also known as N-acetylcysteine (NAC), is a bactericidal properties and break down bacteria biofilms of  clinically relevant pathogenic including pseudomonas aeruginosa,Enterococcus faecalis etc ..

Is a medication that can used as a mucolytic in patients with certain LUNGS condition and as an antidote for ACETAMINOPHEN (Paracetamol) overdose .

Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.14,15,16,17 Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.8,9,10


Acetylcysteine was granted FDA approval on 14 September 1963.


 USED:- 1.overdose of ACETAMINOPHEN ( PARACETAMOL) over dose.

            2.Use in treatment of  obstructive LUNGS disease as an adjuvant treatment.

           3. ACETYLCYSTEINE has been used to complex palladium , to help in dissolve in water . To help to remove palladium from drugs or precursors synthesized by palladium - catalyzed  coupling reaction .

           4.N-acetylcysteine can be used to protect the liver.                                                                                                                                                                             

SIDE EFFECTS:-            The most commonly  reported  adverse effects  for iv formulation of ACETYLCYSTEINE are rash ,urticaria, itching,nousea, vomiting, stomach pain,chest tightness, drowsiness etc 


W) : including in WHO model list of essential medicine March 2011



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